Mosquito-borne Diseases Drug Development Pipeline Review, 2018

Summary

Latest Report Available at Analytical Research Cognizance Mosquito-borne Diseases Drug Market provides pin-point analysis for changing competitive dynamics and a forward looking perspective on different factors driving or restraining industry growth.

Description

This report provides an overview of the pipeline landscape for mosquito-borne diseases and comprehensive information on the therapeutics under development and key players involved in therapeutic development for West Nile virus infections, Japanese encephalitis, yellow fever and malaria. It also features dormant and discontinued products.

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West Nile infection, Japanese encephalitis and yellow fever are all caused by flaviviruses, whereas malaria is caused by a parasite (Plasmodium). Symptoms of West Nile infection include a fever, headache, body aches, skin rash, and swollen lymph glands. There are 18 products in development for this indication.

Japanese encephalitis affects the membranes around the brain. Symptoms include fever, headache, muscle pain, diarrhea, seizures, muscle weakness and paralysis. There are 17 products in development for this indication.

Yellow fever is an acute systemic illness (hemorrhagic fever). Symptoms include irregular heartbeats, bleeding, vomiting, coma, delirium, fever, headache and muscle aches. There are 15 products in development for this indication.

Malaria is a life-threatening blood disease. Symptoms may include fever, chills, headache, sweats, fatigue, enlarged spleen, nausea and vomiting. There are 206 products in development for this indication.

Molecular targets acted on by products in development for mosquito-borne diseases include interferon receptors, toll-like receptors and pathogen proteins such as Plasmodium falciparum merozoite surface proteins. Companies operating in this pipeline space include Sanaria, Medigen and Ology Bioservices.

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Scope
– Which companies are the most active within each pipeline?
– Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
– To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
– What are the most important R&D milestones and data publications to have happened in this disease area?

Reasons to buy
– Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
– Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication and a comprehensive picture of recent updates and milestones for each
– Analyze the companies, institutions and universities currently operating in the pipeline and the products being fielded by each of these
– Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration

Companies Mentioned:
4SC AG
AbbVie Inc
Abivax SA
Adimmune Corp
Agilvax Inc
Akshaya Bio Inc
AlfaSigma SpA
Allergy Therapeutics Plc
Altimmune Inc
Artificial Cell Technologies Inc
AstraZeneca Plc
Bavarian Nordic A/S
Bharat Biotech Ltd
BioCryst Pharmaceuticals Inc
Cadila Healthcare Ltd
Carna Biosciences Inc
Celgene Corp
CEL-SCI Corp
Cilian AG
Curevac AG
Daiichi Sankyo Co Ltd
DesignMedix Inc
DMG Deutsche Malaria GmbH
Eisai Co Ltd
Emergex Vaccines Ltd
Ennaid Therapeutics LLC
Fosun International Ltd

 ……

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Some Points Of Table Of Content:

1 Table of Contents 4
1.1 List of Tables 5
1.2 List of Figures 7

2 Introduction 8
2.1 Mosquito-borne Diseases Report Coverage 8
2.2 West Nile Virus Infections – Overview 8
2.3 Japanese Encephalitis – Overview 8
2.4 Yellow Fever – Overview 8
2.5 Malaria – Overview 8

3 Therapeutics Development 9
3.1 West Nile Virus Infections 9
3.2 Japanese Encephalitis 14
3.3 Yellow Fever 18
3.4 Malaria 22

4 Therapeutics Assessment 38
4.1 West Nile Virus Infections 38
4.2 Japanese Encephalitis 44
4.3 Yellow Fever 47
4.4 Malaria 53

5 Companies Involved in Therapeutics Development 62
5.1 West Nile Virus Infections 62
5.2 Japanese Encephalitis 65
5.3 Yellow Fever 70
5.4 Malaria 74

6 Dormant Projects 102
6.1 West Nile Virus Infections 102
6.2 Japanese Encephalitis 104
6.3 Yellow Fever 105
6.4 Malaria 106

7 Discontinued Products 114
7.1 Japanese Encephalitis 114
7.2 Malaria 114

8 Product Development Milestones 116
8.1 West Nile Virus Infections 116
8.2 Yellow Fever 121
8.3 Malaria 124

9 Appendix 141
9.1 Methodology 141
9.2 Coverage 141
9.3 Secondary Research 141
9.4 Primary Research 141
9.5 Expert Panel Validation 141
9.6 Contact Us 142
9.7 Disclaimer 142

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